Human GZMH protein (Recombinant-Active) (C-10*His) (STJP011910)

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STJP011910-100
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human GZMH-C-10*His protein was developed from mammalian cells and has a target region of C-10*His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: GZMH
Gene ID: 2999
Uniprot ID: GRAH_HUMAN
Immunogen Region: Glu19-Leu246
Immunogen: Homo sapiens (Human)
Function Cytotoxic chymotrypsin-like serine protease with preference for bulky and aromatic residues at the P1 position and acidic residues at the P3' and P4' sites. Probably necessary for target cell lysis in cell-mediated immune responses. Participates in the antiviral response via direct cleavage of several proteins essential for viral replication.
Protein Name Granzyme H
Ccp-X
Cathepsin G-Like 2
Ctsgl2
Cytotoxic T-Lymphocyte Proteinase
Cytotoxic Serine Protease C
Csp-C
Database Links Reactome: R-HSA-2022377
Reactome: R-HSA-381426
Cellular Localisation Cytolytic Granule
Alternative Protein Names Granzyme H protein
Ccp-X protein
Cathepsin G-Like 2 protein
Ctsgl2 protein
Cytotoxic T-Lymphocyte Proteinase protein
Cytotoxic Serine Protease C protein
Csp-C protein
GZMH protein
CGL2 protein
CTSGL2 protein

Information sourced from Uniprot.org

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