Human GSAP protein (Recombinant) (N-His) (STJP003113)

SKU:
STJP003113
€250.20 - €1,396.20
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Short Description :Recombinant-Human GSAP-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:GSAP
Gene ID:54103
Uniprot ID:GSAP_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Asp616-Leu854
Post Translational Modifications The protein is first synthesized as a holoprotein form of 98 kDa and rapidly processed into the gamma-secretase-activating protein 16 kDa C-terminal form, which constitutes the predominant form.
Function Regulator of gamma-secretase activity, which specifically activates the production of amyloid-beta protein (amyloid-beta protein 40 and amyloid-beta protein 42), without affecting the cleavage of other gamma-secretase targets such has Notch. The gamma-secretase complex is an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein). Specifically promotes the gamma-cleavage of APP CTF-alpha (also named APP-CTF) by the gamma-secretase complex to generate amyloid-beta, while it reduces the epsilon-cleavage of APP CTF-alpha, leading to a low production of AICD.
Protein Name Gamma-Secretase-Activating Protein
Gsap
Protein Pigeon Homolog Cleaved Into - Gamma-Secretase-Activating Protein 16 Kda C-Terminal Form
Gsap-16k
Database Links
Cellular Localisation Golgi Apparatus
Trans-Golgi Network
Alternative Protein Names Gamma-Secretase-Activating Protein protein
Gsap protein
Protein Pigeon Homolog Cleaved Into - Gamma-Secretase-Activating Protein 16 Kda C-Terminal Form protein
Gsap-16k protein
GSAP protein
PION protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP005172 Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172) E.coli SDS-PAGE/WB/ELISA/Immunogen
STJP004723 Human WAS protein (Recombinant) (N-His) (STJP004723) E.coli ELISA/Immunogen/SDS-PAGE/WB
STJP015118 Human TAS1R1 protein protein (Recombinant) (N-His) (STJP015118) E.coli ELISA/Immunogen/SDS-PAGE/WB
STJP014345 Human HBZ protein (Recombinant) (N-His) (STJP014345) E.coli ELISA/WB
STJP014302 Human ALDH1A2 protein (Recombinant) (N-His) (STJP014302) E.coli ELISA/WB

Related Products

!