Human GREM2 protein (Recombinant) (N-His) (STJP006359)

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STJP006359
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human GREM2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: GREM2
Gene ID: 64388
Uniprot ID: GREM2_HUMAN
Immunogen Region: Arg22-Gln168
Immunogen: Homo sapiens (Human)
Function Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner, and thereby modulates signaling by BMP family members. Contributes to the regulation of embryonic morphogenesis via BMP family members. Antagonizes BMP4-induced suppression of progesterone production in granulosa cells.
Protein Name Gremlin-2
Cysteine Knot Superfamily 1 - Bmp Antagonist 2
Dan Domain Family Member 3
Protein Related To Dan And Cerberus
Database Links Reactome: R-HSA-201451
Cellular Localisation Secreted
Alternative Protein Names Gremlin-2 protein
Cysteine Knot Superfamily 1 - Bmp Antagonist 2 protein
Dan Domain Family Member 3 protein
Protein Related To Dan And Cerberus protein
GREM2 protein
CKTSF1B2 protein
DAND3 protein
PRDC protein

Information sourced from Uniprot.org

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