| Host: | E.coli |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human GREM2-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | GREM2 |
| Gene ID: | 64388 |
| Uniprot ID: | GREM2_HUMAN |
| Immunogen Region: | Arg22-Gln168 |
| Immunogen: | Homo sapiens (Human) |
| Function | Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner, and thereby modulates signaling by BMP family members. Contributes to the regulation of embryonic morphogenesis via BMP family members. Antagonizes BMP4-induced suppression of progesterone production in granulosa cells. |
| Protein Name | Gremlin-2Cysteine Knot Superfamily 1 - Bmp Antagonist 2Dan Domain Family Member 3Protein Related To Dan And Cerberus |
| Database Links | Reactome: R-HSA-201451 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Gremlin-2 proteinCysteine Knot Superfamily 1 - Bmp Antagonist 2 proteinDan Domain Family Member 3 proteinProtein Related To Dan And Cerberus proteinGREM2 proteinCKTSF1B2 proteinDAND3 proteinPRDC protein |
Information sourced from Uniprot.org