Human GREM1 protein (Recombinant) (N-His) (STJP003319)

Name: Human GREM1 protein (Recombinant) (N-His) (STJP003319)
SKU: STJP003319
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHomo sapiens (Human)

STJP003319

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Short Description	Recombinant-Human GREM1-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications	ELISA/Immunogen/SDS-PAGE/WB
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner. Antagonist of BMP2.inhibits BMP2-mediated differentiation of osteoblasts (in vitro). Acts as inhibitor of monocyte chemotaxis. Can inhibit the growth or viability of normal cells but not transformed cells when is overexpressed.
Protein Name	Gremlin-1 Cell Proliferation-Inducing Gene 2 Protein Cysteine Knot Superfamily 1 - Bmp Antagonist 1 Dan Domain Family Member 2 Down-Regulated In Mos-Transformed Cells Protein Increased In High Glucose Protein 2 Ihg-2
Database Links	Reactome: R-HSA-9830674
Cellular Localisation	Secreted
Alternative Protein Names	Gremlin-1 protein Cell Proliferation-Inducing Gene 2 Protein protein Cysteine Knot Superfamily 1 - Bmp Antagonist 1 protein Dan Domain Family Member 2 protein Down-Regulated In Mos-Transformed Cells Protein protein Increased In High Glucose Protein 2 protein Ihg-2 protein GREM1 protein CKTSF1B1 protein DAND2 protein DRM protein PIG2 protein

Information sourced from Uniprot.org