| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.63ng/mL |
| Detection Limit: | 1.56-100ng/mL |
| Short Description : | This GP1Ba Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma or other biological fluids. |
| Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 4.5 hrs |
| Gene Symbol: | GP1BA |
| Gene ID: | 2811 |
| Uniprot ID: | GP1BA_HUMAN |
| Sample Type: | serum, plasma or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | Glycocalicin is the product of a proteolytic cleavage/shedding, catalyzed by ADAM17, which releases most of the extracellular domain. Binding sites for vWF and thrombin are in this part of the protein. |
| Function | GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the subendothelium. |
| Protein Name | Platelet Glycoprotein Ib Alpha ChainGp-Ib AlphaGpib-AlphaGpibaGlycoprotein IbalphaAntigen Cd42b-AlphaCd Antigen Cd42b Cleaved Into - Glycocalicin |
| Database Links | Reactome: R-HSA-140837Reactome: R-HSA-430116Reactome: R-HSA-75892Reactome: R-HSA-76009Reactome: R-HSA-8936459Reactome: R-HSA-9673221Reactome: R-HSA-9845620Reactome: R-HSA-9846298 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative ELISA Names | Platelet Glycoprotein Ib Alpha Chain ELISA kitGp-Ib Alpha ELISA kitGpib-Alpha ELISA kitGpiba ELISA kitGlycoprotein Ibalpha ELISA kitAntigen Cd42b-Alpha ELISA kitCd Antigen Cd42b Cleaved Into - Glycocalicin ELISA kitGP1BA ELISA kit |
| output |
Information sourced from Uniprot.org
