Human GNRHR protein (Recombinant) (N-GST) (STJP004536)

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STJP004536
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human GNRHR-N-GST protein was developed from e. coli and has a target region of N-GST. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: GNRHR
Gene ID: 2798
Uniprot ID: GNRHR_HUMAN
Immunogen Region: Asp185-Thr281
Immunogen: Homo sapiens (Human)
Function Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 may act as an inhibitor of GnRH-R signaling.
Protein Name Gonadotropin-Releasing Hormone Receptor
Gnrh Receptor
Gnrh-R
Database Links Reactome: R-HSA-375281
Reactome: R-HSA-416476
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Gonadotropin-Releasing Hormone Receptor protein
Gnrh Receptor protein
Gnrh-R protein
GNRHR protein
GRHR protein

Information sourced from Uniprot.org