| Host: | E.coli |
| Applications: | SDS-PAGE |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human Glutathione S-transferase mu 4/GSTM4-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol, 50mM NaCl |
| Concentration: | 1 mg/mL |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GSTM4 |
| Gene ID: | 2948 |
| Uniprot ID: | GSTM4_HUMAN |
| Immunogen Region: | 1-218aa |
| Accession Number: | NP_000841 |
| Immunogen: | Human |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MSMTLGYWDI RGLAHAIRLL LEYTDSSYEE KKYTMGDAPD YDRSQWLNEK FKLGLDFPNL PYLIDGAHKI TQSNAILCYI ARKHNLCGET EEEKIRVDIL ENQAMDVSNQ LARVCYSPDF EKLKPEYLEE LPTMMQHFSQ FLGKRPWFVG DKITFVDFLA YDVLDLHRIF EPNCLDAFPN LKDFISRFEG LEKISAYMKS SRFLPKPL |
| Tissue Specificity | Expressed in a wide variety of tissues. |
| Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Catalyzes the conjugation of leukotriene A4 with reduced glutathione (GSH) to form leukotriene C4. Can also catalyze the transfer of a glutathionyl group from glutathione (GSH) to 13(S),14(S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator that possess potent anti-inflammatory and proresolving actions. |
| Protein Name | Glutathione S-Transferase Mu 4Gst Class-Mu 4Gst-Mu2Gstm4-4Leukotriene C4 Synthase Gstm4 |
| Database Links | Reactome: R-HSA-156590Reactome: R-HSA-9026762 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Glutathione S-Transferase Mu 4 proteinGst Class-Mu 4 proteinGst-Mu2 proteinGstm4-4 proteinLeukotriene C4 Synthase Gstm4 proteinGSTM4 protein |
Information sourced from Uniprot.org