Human Glutathione S-transferase mu 1/GSTM1 protein (Recombinant) (His-Tag) (STJP018710)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Glutathione S-transferase mu 1/GSTM1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GSTM1 |
| Gene ID | 2944 |
| Uniprot ID | GSTM1_HUMAN |
| Accession Number | NP_666533 |
| Immunogen | Human |
| Immunogen Region | 1-181aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH RSMPMILGYW DIRGLAHAIR LLLEYTDSSY EEKKYTMGDA PDYDRSQWLN EKFKLGLDFP NLPYLIDGAH KITQSNAILC YIARKHNLCG ETEEEKIRVD ILENQTMDNH MQLGMICYNP EFEKLKPKYL EELPEKLKLY SEFLGKRPWF AGNKGLEKIS AYMKSSRFLP RPVFSKMAVW GNK |
Additional Info
| Tissue Specificity | Liver (at protein level). |
| Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. |
| Protein Name | Glutathione S-Transferase Mu 1Gst Hb Subunit 4Gst Class-Mu 1Gstm1-1Gstm1a-1aGstm1b-1bGth4 |
| Database Links | Reactome: R-HSA-156590Reactome: R-HSA-9748787Reactome: R-HSA-9753281 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Glutathione S-Transferase Mu 1 proteinGst Hb Subunit 4 proteinGst Class-Mu 1 proteinGstm1-1 proteinGstm1a-1a proteinGstm1b-1b proteinGth4 proteinGSTM1 proteinGST1 protein |
Information sourced from Uniprot.org