| Short Description : | Recombinant-Human Glutaredoxin 5/GLRX5-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 0.5 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 0.1M NaCl |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GLRX5 |
| Gene ID: | 51218 |
| Uniprot ID: | GLRX5_HUMAN |
| Accession Number: | NP_057501 |
| Immunogen: | Human |
| Immunogen Region: | 1-157aa |
| Immunogen Sequence: |
| Function | Monothiol glutaredoxin involved in mitochondrial iron-sulfur (Fe/S) cluster transfer. Receives 2Fe/2S clusters from scaffold protein ISCU and mediates their transfer to apoproteins, to the 4Fe/FS cluster biosynthesis machinery, or export from mitochondrion. Required for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1. |
| Protein Name | Glutaredoxin-Related Protein 5 - MitochondrialMonothiol Glutaredoxin-5 |
| Database Links | Reactome: R-HSA-1362409 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Protein Names | Glutaredoxin-Related Protein 5 - Mitochondrial proteinMonothiol Glutaredoxin-5 proteinGLRX5 proteinC14orf87 protein |
Information sourced from Uniprot.org
