Human Glutaredoxin 3/GLRX3 protein (Recombinant) (His-Tag) (STJP016691)

SKU:
STJP016691
€150.60 - €779.40
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human Glutaredoxin 3/GLRX3-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 1mM DTT
Concentration: 0.5 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: GLRX3
Gene ID: 10539
Uniprot ID: GLRX3_HUMAN
Immunogen Region: 1-335aa
Accession Number: NP_006532
Immunogen: Human
Immunogen Sequence: MGSSHHHHHH SSGLVPRGSH MAAGAAEAAV AAVEEVGSAG QFEELLRLKA KSLLVVHFWA PWAPQCAQMN EVMAELAKEL PQVSFVKLEA EGVPEVSEKY EISSVPTFLF FKNSQKIDRL DGAHAPELTK KVQRHASSGS FLPSANEHLK EDLNLRLKKL THAAPCMLFM KGTPQEPRCG FSKQMVEILH KHNIQFSSFD IFSDEEVRQG LKAYSSWPTY PQLYVSGE
Tissue Specificity Expressed in heart, spleen, testis and, to a lower extent, in thymus and peripheral blood leukocytes. Weakly expressed in lung, placenta, colon and small intestine.
Function Together with BOLA2, acts as a cytosolic iron-sulfur (Fe-S) cluster assembly factor that facilitates 2Fe-2S cluster insertion into a subset of cytosolic proteins. Acts as a critical negative regulator of cardiac hypertrophy and a positive inotropic regulator. Required for hemoglobin maturation. Does not possess any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity.
Protein Name Glutaredoxin-3
Pkc-Interacting Cousin Of Thioredoxin
Picot
Pkc-Theta-Interacting Protein
Pkcq-Interacting Protein
Thioredoxin-Like Protein 2
Database Links Reactome: R-HSA-917937
Cellular Localisation Cytoplasm
Cytosol
Cell Cortex
Myofibril
Sarcomere
Z Line
Under The Plasma Membrane
After Pma Stimulation
Glrx3 And Prkcq/Pkc-Theta Translocate To A More Extended Submembrane Area
In The Z Line
Found Associated With Csrp3
Alternative Protein Names Glutaredoxin-3 protein
Pkc-Interacting Cousin Of Thioredoxin protein
Picot protein
Pkc-Theta-Interacting Protein protein
Pkcq-Interacting Protein protein
Thioredoxin-Like Protein 2 protein
GLRX3 protein
PICOT protein
TXNL2 protein
HUSSY-22 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP016684 Human Glutaredoxin 5/GLRX5 protein (Recombinant) (His-Tag) (STJP016684) E.coli SDS-PAGE
STJP016578 Human Glutaredoxin 2/GLRX2 protein (Recombinant) (His-Tag) (STJP016578) E.coli SDS-PAGE
STJP003396 Human GLRX3 protein (Recombinant) (N-His) (STJP003396) E.coli ELISA/Immunogen/SDS-PAGE/WB
STJE0020358 Human GLRX3 (Glutaredoxin 3) Sandwich ELISA Kit (STJE0020358) Human ELISA
STJP019646 Human Glutaredoxin 1/GLRX1 protein (Recombinant) (No-Tag) (STJP019646) E.coli SDS-PAGE

Related Products

!