Human GLRX3 protein (Recombinant) (N-His) (STJP003396)

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STJP003396
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human GLRX3-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: GLRX3
Gene ID: 10539
Uniprot ID: GLRX3_HUMAN
Immunogen Region: Val10-Ser117
Immunogen: Homo sapiens (Human)
Function Together with BOLA2, acts as a cytosolic iron-sulfur (Fe-S) cluster assembly factor that facilitates 2Fe-2S cluster insertion into a subset of cytosolic proteins. Acts as a critical negative regulator of cardiac hypertrophy and a positive inotropic regulator. Required for hemoglobin maturation. Does not possess any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity.
Protein Name Glutaredoxin-3
Pkc-Interacting Cousin Of Thioredoxin
Picot
Pkc-Theta-Interacting Protein
Pkcq-Interacting Protein
Thioredoxin-Like Protein 2
Database Links Reactome: R-HSA-917937
Cellular Localisation Cytoplasm
Cytosol
Cell Cortex
Myofibril
Sarcomere
Z Line
Under The Plasma Membrane
After Pma Stimulation
Glrx3 And Prkcq/Pkc-Theta Translocate To A More Extended Submembrane Area
In The Z Line
Found Associated With Csrp3
Alternative Protein Names Glutaredoxin-3 protein
Pkc-Interacting Cousin Of Thioredoxin protein
Picot protein
Pkc-Theta-Interacting Protein protein
Pkcq-Interacting Protein protein
Thioredoxin-Like Protein 2 protein
GLRX3 protein
PICOT protein
TXNL2 protein
HUSSY-22 protein

Information sourced from Uniprot.org

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