Human GGH protein (Recombinant) (His-Tag) (STJP017522)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human GGH-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol, 0.1M NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GGH |
| Gene ID | 8836 |
| Uniprot ID | GGH_HUMAN |
| Accession Number | NP_003869.1 |
| Immunogen | Human |
| Immunogen Region | 25-318aa |
| Immunogen Sequence |
Additional Info
| Function | Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates. |
| Protein Name | Gamma-Glutamyl HydrolaseConjugaseGhGamma-Glu-X Carboxypeptidase |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | SecretedExtracellular SpaceLysosomeMelanosomeWhile Its Intracellular Location Is Primarily The LysosomeMost Of The Enzyme Activity Is SecretedIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Protein Names | Gamma-Glutamyl Hydrolase proteinConjugase proteinGh proteinGamma-Glu-X Carboxypeptidase proteinGGH protein |
Information sourced from Uniprot.org