• Human GDNFR-alpha-1/GFRA1 protein (Recombinant) (C-hFc&His) (STJP000878)
  • Human GDNFR-alpha-1/GFRA1 protein (Recombinant) (C-hFc&His) (STJP000878)
  • Human GDNFR-alpha-1/GFRA1 protein (Recombinant) (C-hFc&His) (STJP000878)
  • Human GDNFR-alpha-1/GFRA1 protein (Recombinant) (C-hFc&His) (STJP000878)

Human GDNFR-alpha-1/GFRA1 protein (Recombinant) (C-hFc&His) (STJP000878)

SKU:
STJP000878

£72.50 - £105.50
Current Stock:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human GDNFR-alpha-1/GFRA1-C-hFc&His protein was developed from hek293 cells and has a target region of C-hFc&His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Immunoreactivity: Measured by its binding ability in a functional ELISA. Immobilized Human GDNF at 1 Mu g/mL (100 Mu L/well) can bind Human GFRA1 with a linear range of 2-332 ng/mL.
Gene Symbol: GFRA1
Gene ID: 2674
Uniprot ID: GFRA1_HUMAN
Immunogen: Recombinant Human GDNFR-alpha-1/GFRA1 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Ala19-Lys429) of human GFRA1/GFR Alpha 1/GDNFRA (Accession #NP_665736) fused with an Fc, 6×His tag at the C-terminus
Function Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor.
Protein Name Gdnf Family Receptor Alpha-1
Gdnf Receptor Alpha-1
Gdnfr-Alpha-1
Gfr-Alpha-1
Ret Ligand 1
Tgf-Beta-Related Neurotrophic Factor Receptor 1
Database Links Reactome: R-HSA-419037
Reactome: R-HSA-5673001
Reactome: R-HSA-8853659
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Golgi Apparatus
Trans-Golgi Network
Endosome
Multivesicular Body
Localizes Mainly To The Plasma Membrane
In The Presence Of Sorl1
Shifts To Vesicular Structures
Including Trans-Golgi Network
Endosomes And Multivesicular Bodies
Alternative Protein Names Gdnf Family Receptor Alpha-1 protein
Gdnf Receptor Alpha-1 protein
Gdnfr-Alpha-1 protein
Gfr-Alpha-1 protein
Ret Ligand 1 protein
Tgf-Beta-Related Neurotrophic Factor Receptor 1 protein
GFRA1 protein
GDNFRA protein
RETL1 protein
TRNR1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance