| Host: | Mouse/Goat |
| Applications: | ELISA |
| Reactivity: | Human |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description : | This GDNF antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Clonality : | Monoclonal/Polyclonal |
| Conjugation: | Unconjugated/Biotin |
| Formulation: | Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4. |
| Purification: | Capture Purification: Protein A or G.Detection Purification: Antigen Affinity. |
| Concentration: | 0.5 mg/mL |
| Storage Instruction: | Store at-20°C for long term, and avoid freeze-thaw cycles. |
| Gene Symbol: | GDNF |
| Gene ID: | 2668 |
| Uniprot ID: | GDNF_HUMAN |
| Immunogen: | Capture immunogen: Recombinant Human GDNF protein.Detection Immunogen: Recombinant Human GDNF protein. |
| Function | Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. Acts by binding to its coreceptor, GFRA1, leading to autophosphorylation and activation of the RET receptor. Involved in the development of the neural crest. |
| Protein Name | Glial Cell Line-Derived Neurotrophic FactorHgdnfAstrocyte-Derived Trophic FactorAtf |
| Database Links | Reactome: R-HSA-419037Reactome: R-HSA-5673001Reactome: R-HSA-8853659Reactome: R-HSA-9830674 |
| Cellular Localisation | Secreted |
| Alternative Antibody Pair Names | Glial Cell Line-Derived Neurotrophic Factor antibody pairHgdnf antibody pairAstrocyte-Derived Trophic Factor antibody pairAtf antibody pairGDNF antibody pair |
Information sourced from Uniprot.org
