Host: | Mouse/Goat |
Applications: | ELISA |
Reactivity: | Human |
Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Short Description : | This GDF2 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
Clonality : | Monoclonal/Polyclonal |
Conjugation: | Unconjugated/Biotin |
Formulation: | Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4. |
Purification: | Capture Purification: Protein A or G.Detection Purification: Antigen Affinity. |
Concentration: | 0.5 mg/mL |
Storage Instruction: | Store at-20°C for long term, and avoid freeze-thaw cycles. |
Gene Symbol: | GDF2 |
Gene ID: | 2658 |
Uniprot ID: | GDF2_HUMAN |
Immunogen: | Capture immunogen: Recombinant Human GDF2 protein.Detection Immunogen: Recombinant Human GDF2 protein. |
Post Translational Modifications | A reversible disulfide bond can be formed between the two subunits in the homodimer.this has no effect on GDF2 activity. |
Function | Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG. |
Protein Name | Growth/Differentiation Factor 2Gdf-2Bone Morphogenetic Protein 9Bmp-9 |
Database Links | Reactome: R-HSA-201451 |
Cellular Localisation | Secreted |
Alternative Antibody Pair Names | Growth/Differentiation Factor 2 antibody pairGdf-2 antibody pairBone Morphogenetic Protein 9 antibody pairBmp-9 antibody pairGDF2 antibody pairBMP9 antibody pair |
Information sourced from Uniprot.org