Human GCAT protein (Recombinant) (His-Tag) (STJP018189)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP018189
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General Information

Short DescriptionRecombinant-Human GCAT-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE/Denatured
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration1 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% Glycerol
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolGCAT
Gene ID23464
Uniprot IDKBL_HUMAN
Accession NumberNP_055106
ImmunogenHuman
Immunogen Region22-419aa
Immunogen SequenceSALAQLRGI LEGELEGIRG AGTWKSERVI TSRQGPHIRV DGVSGGILNF CANNYLGLSS HPEVIQAGLQ ALEEFGAGLS SVRFICGTQS IHKNLEAKIA RFHQREDAIL YPSCYDANAG LFEALLTPED AVLSDELNHA SIIDGIRLCK AHKYRYRHLD MADLEAKLQE AQKHRLRLVA TDGAFSMDGD IAPLQEICCL ASRYGA

Additional Info

Tissue Specificity Strongly expressed in heart, brain, liver and pancreas. Also found in lung.
Function Pyridoxal phosphate (PLP) dependent enzyme, which catalyzes the cleavage of 2-amino-3-oxobutanoate to glycine and acetyl-CoA.
Protein Name 2-Amino-3-Ketobutyrate Coenzyme A Ligase - Mitochondrial
Akb Ligase
Aminoacetone Synthase
Glycine Acetyltransferase
Database Links Reactome: R-HSA-8849175
Cellular Localisation Mitochondrion
Nucleus
Translocates To The Nucleus Upon Cold And Osmotic Stress
Alternative Protein Names 2-Amino-3-Ketobutyrate Coenzyme A Ligase - Mitochondrial protein
Akb Ligase protein
Aminoacetone Synthase protein
Glycine Acetyltransferase protein
GCAT protein
KBL protein

Information sourced from Uniprot.org

Citations

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