Human GBP4 protein (Recombinant) (N-His) (STJP005861)

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STJP005861
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human GBP4-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: GBP4
Gene ID: 115361
Uniprot ID: GBP4_HUMAN
Immunogen Region: Met1-Lys292
Immunogen: Homo sapiens (Human)
Function Interferon (IFN)-inducible GTPase that plays important roles in innate immunity against a diverse range of bacterial, viral and protozoan pathogens. Negatively regulates the antiviral response by inhibiting activation of IRF7 transcription factor.
Protein Name Guanylate-Binding Protein 4
Gtp-Binding Protein 4
Gbp-4
Guanine Nucleotide-Binding Protein 4
Database Links Reactome: R-HSA-877300
Cellular Localisation Golgi Apparatus Membrane
Cytoplasm
Nucleus
Perinuclear Region
Heterodimers With Gbp1
Gbp2 And Gbp5 Localize In The Compartment Of The Prenylated Gbps: With Gbp1 In A Vesicle-Like Compartment
With Gbp2
Around The Nucleus And With Gbp5
At The Golgi Apparatus
Alternative Protein Names Guanylate-Binding Protein 4 protein
Gtp-Binding Protein 4 protein
Gbp-4 protein
Guanine Nucleotide-Binding Protein 4 protein
GBP4 protein

Information sourced from Uniprot.org

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