Human GAS2 protein (Recombinant) (N-His) (STJP003298)

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STJP003298
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human GAS2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: GAS2
Gene ID: 2620
Uniprot ID: GAS2_HUMAN
Immunogen Region: Gly64-Asp267
Immunogen: Homo sapiens (Human)
Post Translational Modifications Cleaved, during apoptosis, on a specific aspartic residue by caspases. Phosphorylated on serine residues during the G0-G1 transition phase.
Function Required to maintain microtubule bundles in inner ear supporting cells, affording them with mechanical stiffness to transmit sound energy through the cochlea.
Protein Name Growth Arrest-Specific Protein 2
Gas-2
Database Links Reactome: R-HSA-264870
Cellular Localisation Cytoplasm
Cytoskeleton
Stress Fiber
Membrane
Peripheral Membrane Protein
Component Of The Microfilament System
Colocalizes With Actin Fibers At The Cell Border And Along The Stress Fibers In Growth-Arrested Fibroblasts
Mainly Membrane-Associated
When Hyperphosphorylated
Accumulates At Membrane Ruffles
Colocalizes With Detyrosinated Alpha-Tubulin Along The Length Of Microtubule Bundles In Inner And Outer Pillar Cells
Alternative Protein Names Growth Arrest-Specific Protein 2 protein
Gas-2 protein
GAS2 protein

Information sourced from Uniprot.org

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