Human GADD45 alpha protein (Recombinant) (His-Tag) (STJP016688)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human GADD45 alpha-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 0.1M NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GADD45A |
| Gene ID | 1647 |
| Uniprot ID | GA45A_HUMAN |
| Accession Number | NP_001915 |
| Immunogen | Human |
| Immunogen Region | 1-165aa |
| Immunogen Sequence | MTLEEFSAGE QKTERMDKVG DALEEVLSKA LSQRTITVGV YEAAKLLNVD PDNVVLCLLA ADEDDDRDVA LQIHFTLIQA FCCENDINIL RVSNPGRLAE LLLLETDAGP AASEGAEQPP DLHCVLVTNP HSSQWKDPAL SQLICFCRES RYMDQWVPVI NLPER |
Additional Info
| Function | In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity. Might affect PCNA interaction with some CDK (cell division protein kinase) complexes.stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. |
| Protein Name | Growth Arrest And Dna Damage-Inducible Protein Gadd45 AlphaDna Damage-Inducible Transcript 1 ProteinDdit-1 |
| Database Links | Reactome: R-HSA-6804114Reactome: R-HSA-9617828 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Growth Arrest And Dna Damage-Inducible Protein Gadd45 Alpha proteinDna Damage-Inducible Transcript 1 Protein proteinDdit-1 proteinGADD45A proteinDDIT1 proteinGADD45 protein |
Information sourced from Uniprot.org