Human G-CSF protein (Recombinant) (STJP000230)

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STJP000230

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Host: CHO cells
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human G-CSF-protein was developed from cho cells. For use in research applications.
Conjugation: Unconjugated
Formulation: Lyophilised from 0.2 Mu m filtered PBS solution pH7.0.
Dilution Range: Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers.
Storage Instruction: Can be stored in working aliquots at°C-°C C for one month, or at-20°C C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. NA
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than.1 ng/µg (1EU/µg). NA
Immunoreactivity: The ED (50) was determined by the dose-dependent proliferation of murine M-NFS-60 cells is ≤.1 ng/ml, corresponding to a specific activity of ≥ xunits/mg. NA
Gene Symbol: CSF3
Gene ID: 1440
Uniprot ID: CSF3_HUMAN
Immunogen Region: Mature chain
Immunogen: Optimized DNA sequence encoding Human G-CSF mature chain was expressed in CHO Cells NA
Immunogen Sequence: MAGPATQSPM KLMALQLLLW HSALWTVQEA TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA LQEKLCA TYKLCHPEEL VLLGHSLGIP WAPLSSCPSQ ALQLAGCLSQ LHSGLFLYQG LLQALEGISP ELGPTLDTLQ LDVADFATTI WQQMEELGMA PALQPTQGAM PAFASAFQRR AGGVLVASHL QSFLEVSYRV LRHLAQP NA
Post Translational Modifications O-glycan consists of Gal-GalNAc disaccharide which can be modified with up to two sialic acid residues (done in recombinantly expressed G-CSF from CHO cells).
Function Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.
Protein Name Granulocyte Colony-Stimulating Factor
G-Csf
Pluripoietin
Filgrastim
Lenograstim
Database Links Reactome: R-HSA-449836
Reactome: R-HSA-6783783
Reactome: R-HSA-9674555
Reactome: R-HSA-9705462
Cellular Localisation Secreted
Alternative Protein Names Granulocyte Colony-Stimulating Factor protein
G-Csf protein
Pluripoietin protein
Filgrastim protein
Lenograstim protein
CSF3 protein
C17orf33 protein
GCSF protein

Information sourced from Uniprot.org

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