Human G-CSF/CSF3 protein (Recombinant) (C-6His) (STJP001902)

SKU:
STJP001902
£104.50 - £347.50
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Short Description :Recombinant-Human G-CSF/CSF3-C-6His protein was developed in hek293 cells using the region Met1-Pro204. For use in research applications.
Host:HEK293 cells
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation:Unconjugated
Formulation:Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunoreactivity:1.Measured in a cell proliferation assay using NFS-60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is 41-164 pg/mL.
Determination Method:<0.001 EU/Mu g
Gene Symbol:CSF3
Gene ID:1440
Uniprot ID:CSF3_HUMAN
Immunogen:Recombinant Human G-CSF/CSF3 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Pro204) of human G-CSF/CSF3 (Accession #NP_757373.1) fused with and a 6×His tag at the C-terminus.
Immunogen Region:Met1-Pro204
Immunogen Sequence:MAGPATQSPMKLMALQLLLW HSALWTVQEATPLGPASSLP QSFLLKCLEQVRKIQGDGAA LQEKLCATYKLCHPEELVLL GHSLGIPWAPLSSCPSQALQ LAGCLSQLHSGLFLYQGLLQ ALEGISPELGPTLDTLQLDV ADFATTIWQQMEELGMAPAL QPTQGAMPAFASAFQRRAGG VLVASHLQSFLEVSYRVLRH LAQP
Function Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.
Protein Name Granulocyte Colony-Stimulating Factor
G-Csf
Pluripoietin
Filgrastim
Lenograstim
Database Links Reactome: R-HSA-449836
Reactome: R-HSA-6783783
Reactome: R-HSA-9674555
Reactome: R-HSA-9705462
Cellular Localisation Secreted
Alternative Protein Names Granulocyte Colony-Stimulating Factor protein
G-Csf protein
Pluripoietin protein
Filgrastim protein
Lenograstim protein
CSF3 protein
C17orf33 protein
GCSF protein

Information sourced from Uniprot.org