| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | ＜0.001 EU/Mu g |
| Immunoreactivity: | 1.Measured in a cell proliferation assay using NFS-60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is 41-164 pg/mL. |
| Gene Symbol: | CSF3 |
| Gene ID: | 1440 |
| Uniprot ID: | CSF3_HUMAN |
| Immunogen Region: | Met1-Pro204 |
| Immunogen: | Recombinant Human G-CSF/CSF3 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Pro204) of human G-CSF/CSF3 (Accession #NP_757373.1) fused with and a 6×His tag at the C-terminus. |
| Immunogen Sequence: | MAGPATQSPMKLMALQLLLW HSALWTVQEATPLGPASSLP QSFLLKCLEQVRKIQGDGAA LQEKLCATYKLCHPEELVLL GHSLGIPWAPLSSCPSQALQ LAGCLSQLHSGLFLYQGLLQ ALEGISPELGPTLDTLQLDV ADFATTIWQQMEELGMAPAL QPTQGAMPAFASAFQRRAGG VLVASHLQSFLEVSYRVLRH LAQP |
| Function | Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. |
| Protein Name | Granulocyte Colony-Stimulating FactorG-CsfPluripoietinFilgrastimLenograstim |
| Database Links | Reactome: R-HSA-449836Reactome: R-HSA-6783783Reactome: R-HSA-9674555Reactome: R-HSA-9705462 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Granulocyte Colony-Stimulating Factor proteinG-Csf proteinPluripoietin proteinFilgrastim proteinLenograstim proteinCSF3 proteinC17orf33 proteinGCSF protein |
Information sourced from Uniprot.org
