Human FTSJ2 protein (Recombinant) (His-Tag) (STJP017811)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human FTSJ2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MRM2 |
| Gene ID | 29960 |
| Uniprot ID | MRM2_HUMAN |
| Accession Number | NP_037525 |
| Immunogen | Human |
| Immunogen Region | 51-246aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Widely expressed, with highest expression in muscle, placenta, and heart. |
| Function | S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methyluridine at position 1369 (Um1369) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA. This activity may require prior 2'-O-methylguanosine modification at position 1370 (Gm1370) by MRM3. Essential for late-stage assembly of mtLSU required for efficient translation of mitochondrial DNA encoded proteins.methyltransferase activity is not required for this function. Essential for mitochondrial respiratory function. |
| Protein Name | Rrna Methyltransferase 2 - Mitochondrial16s RrnaUridine(1369-2'-O-Methyltransferase16s Rrna Um1369 2'-O-MethyltransferaseProtein Ftsj Homolog 2 |
| Database Links | Reactome: R-HSA-6793080 |
| Cellular Localisation | Mitochondrion |
| Alternative Protein Names | Rrna Methyltransferase 2 - Mitochondrial protein16s Rrna proteinUridine(1369-2'-O-Methyltransferase protein16s Rrna Um1369 2'-O-Methyltransferase proteinProtein Ftsj Homolog 2 proteinMRM2 proteinFJH1 proteinFTSJ2 protein |
Information sourced from Uniprot.org