Human FOLR2 (Folate Receptor 2, Adult) Sandwich ELISA Kit (STJE0008962)
SPECIFICATIONS
General Information
| Short Description | This FOLR2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.064ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | FOLR2 |
| Gene ID | 2350 |
| Uniprot ID | FOLR2_HUMAN |
| Sample Type | serum, plasma, tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Expressed in placenta and hematopoietic cells. Expression is increased in malignant tissues. |
| Post Translational Modifications | N-glycosylated. |
| Function | Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. |
| Protein Name | Folate Receptor BetaFr-BetaFolate Receptor 2Folate Receptor - Fetal/PlacentalPlacental Folate-Binding ProteinFbp |
| Database Links | Reactome: R-HSA-163125Reactome: R-HSA-196757 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorSecreted |
| Alternative ELISA Names | Folate Receptor Beta ELISA kitFr-Beta ELISA kitFolate Receptor 2 ELISA kitFolate Receptor - Fetal/Placental ELISA kitPlacental Folate-Binding Protein ELISA kitFbp ELISA kitFOLR2 ELISA kit |
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Information sourced from Uniprot.org