Human FOLR2 (Folate Receptor 2, Adult) Sandwich ELISA Kit (STJE0008962)

Human FOLR2 (Folate Receptor 2, Adult) Sandwich ELISA Kit (STJE0008962)

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STJE0008962
£421.50 - £586.50
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Short Description :This FOLR2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids..
Applications:ELISA
Reactivity:Human
Sensitivity:0.064ng/mL
Detection Limit:0.156-10ng/mL
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Storage Instruction:Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:4.5 hrs
Gene Symbol:FOLR2
Gene ID:2350
Uniprot ID:FOLR2_HUMAN
Sample Type:serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Expressed in placenta and hematopoietic cells. Expression is increased in malignant tissues.
Post Translational Modifications N-glycosylated.
Function Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release.
Protein Name Folate Receptor Beta
Fr-Beta
Folate Receptor 2
Folate Receptor - Fetal/Placental
Placental Folate-Binding Protein
Fbp
Database Links Reactome: R-HSA-163125
Reactome: R-HSA-196757
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Secreted
Alternative ELISA Names Folate Receptor Beta ELISA kit
Fr-Beta ELISA kit
Folate Receptor 2 ELISA kit
Folate Receptor - Fetal/Placental ELISA kit
Placental Folate-Binding Protein ELISA kit
Fbp ELISA kit
FOLR2 ELISA kit
output

Information sourced from Uniprot.org

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