| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 0.1 EU/Mu g of the protein by LAL method. |
| Immunoreactivity: | Measured by its binding ability in a functional ELISA. Immobilized recombinant Human Inhibin beta A at 0.5 Mu g/mL (100 Mu L/well) can bind recombinant Human FST, the EC50 of Human FST is 7.1 ng/mL. |
| Gene Symbol: | FST |
| Gene ID: | 10468 |
| Uniprot ID: | FST_HUMAN |
| Immunogen: | Active Recombinant Human Follistatin/FST Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly30-Trp344) of human Follistatin (Accession #NP_037541.1) fused with a 6×His tag at the C-terminus. |
| Immunogen Sequence: | GNCWLRQAKNGRCQVLYKTE LSKEECCSTGRLSTSWTEED VNDNTLFKWMIFNGGAPNCI PCKETCENVDCGPGKKCRMN KKNKPRCVCAPDCSNITWKG PVCGLDGKTYRNECALLKAR CKEQPELEVQYQGRCKKTCR DVFCPGSSTCVVDQTNNAYC VTCNRICPEPASSEQYLCGN DGVTYSSACHLRKATCLLGR SIGLAYEGKCIKAKSCEDIQ CTGGKKCLWDFKVGRGRCS |
| Function | Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH). |
| Protein Name | FollistatinFsActivin-Binding Protein |
| Database Links | Reactome: R-HSA-2473224 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Follistatin proteinFs proteinActivin-Binding Protein proteinFST protein |
Information sourced from Uniprot.org