Human FOLH1/PSMA protein (Recombinant-Active) (N-His) (STJP012642)

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STJP012642-100
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Short Description :Recombinant-Active-Human FOLH1/PSMA-N-His protein was developed from mammalian cells and has a target region of N-His. For use in research applications.
Applications:ELISA/WB
Host:Mammalian Cells
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation:Unconjugated
Formulation:Supplied as a 0.22 Mu m filtered solution in 20mM MES, 150mM NaCl, 5% Trehalose, pH 5.5.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:< 1 EU/µg as determined by LAL test.
Gene Symbol:FOLH1
Gene ID:2346
Uniprot ID:FOLH1_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Lys44-Ala750
Post Translational Modifications The first two amino acids at the N-terminus of isoform PSMA' appear to be cleaved by limited proteolysis. The N-terminus is blocked.
Function Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression. Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.
Protein Name Glutamate Carboxypeptidase 2
Cell Growth-Inhibiting Gene 27 Protein
Folate Hydrolase 1
Folylpoly-Gamma-Glutamate Carboxypeptidase
Fgcp
Glutamate Carboxypeptidase Ii
Gcpii
Membrane Glutamate Carboxypeptidase
Mgcp
N-Acetylated-Alpha-Linked Acidic Dipeptidase I
Naaladase I
Prostate-Specific Membrane Antigen
Psm
Psma
Pteroylpoly-Gamma-Glutamate Carboxypeptidase
Database Links Reactome: R-HSA-8963693
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Isoform Psma': Cytoplasm
Alternative Protein Names Glutamate Carboxypeptidase 2 protein
Cell Growth-Inhibiting Gene 27 Protein protein
Folate Hydrolase 1 protein
Folylpoly-Gamma-Glutamate Carboxypeptidase protein
Fgcp protein
Glutamate Carboxypeptidase Ii protein
Gcpii protein
Membrane Glutamate Carboxypeptidase protein
Mgcp protein
N-Acetylated-Alpha-Linked Acidic Dipeptidase I protein
Naaladase I protein
Prostate-Specific Membrane Antigen protein
Psm protein
Psma protein
Pteroylpoly-Gamma-Glutamate Carboxypeptidase protein
FOLH1 protein
FOLH protein
NAALAD1 protein
PSM protein
PSMA protein
GIG27 protein

Information sourced from Uniprot.org

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