Human FNTA protein (Recombinant) (N-His) (STJP004811)

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STJP004811
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human FNTA-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: FNTA
Gene ID: 2339
Uniprot ID: FNTA_HUMAN
Immunogen Region: Met51-Lys366
Immunogen: Homo sapiens (Human)
Function Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation.
Protein Name Protein Farnesyltransferase/Geranylgeranyltransferase Type-1 Subunit Alpha
Caax Farnesyltransferase Subunit Alpha
Ftase-Alpha
Ras Proteins Prenyltransferase Subunit Alpha
Type I Protein Geranyl-Geranyltransferase Subunit Alpha
Ggtase-I-Alpha
Database Links Reactome: R-HSA-111465
Reactome: R-HSA-2514859
Reactome: R-HSA-9648002
Reactome: R-HSA-9679191
Alternative Protein Names Protein Farnesyltransferase/Geranylgeranyltransferase Type-1 Subunit Alpha protein
Caax Farnesyltransferase Subunit Alpha protein
Ftase-Alpha protein
Ras Proteins Prenyltransferase Subunit Alpha protein
Type I Protein Geranyl-Geranyltransferase Subunit Alpha protein
Ggtase-I-Alpha protein
FNTA protein

Information sourced from Uniprot.org

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