| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.115ng/mL |
| Detection Limit: | 0.312-20ng/mL |
| Short Description: | This FMO1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.. |
| Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 4.5 hrs |
| Gene Symbol: | FMO1 |
| Gene ID: | 2326 |
| Uniprot ID: | FMO1_HUMAN |
| Sample Type: | tissue homogenates or other biological fluids. |
| Tissue Specificity | Expressed mainly in fetal and adult liver. |
| Post Translational Modifications | |
| Function | Broad spectrum monooxygenase that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including xenobiotics. Catalyzes the S-oxygenation of hypotaurine to produce taurine, an organic osmolyte involved in cell volume regulation as well as a variety of cytoprotective and developmental processes. In vitro, catalyzes the N-oxygenation of trimethylamine (TMA) to produce trimethylamine N-oxide (TMAO) and could therefore participate to the detoxification of this compound that is generated by the action of gut microbiota from dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. |
| Protein Name | Flavin-Containing Monooxygenase 1 Dimethylaniline Monooxygenase N-Oxide-Forming 1 Dimethylaniline Oxidase 1 Fetal Hepatic Flavin-Containing Monooxygenase 1 Fmo 1 Trimethylamine Monooxygenase |
| Database Links | Reactome: R-HSA-1614558 Reactome: R-HSA-217271 |
| Cellular Localisation | Endoplasmic Reticulum Membrane Single-Pass Membrane Protein |
| Alternative ELISA Names | Flavin-Containing Monooxygenase 1 ELISA kit Dimethylaniline Monooxygenase N-Oxide-Forming 1 ELISA kit Dimethylaniline Oxidase 1 ELISA kit Fetal Hepatic Flavin-Containing Monooxygenase 1 ELISA kit Fmo 1 ELISA kit Trimethylamine Monooxygenase ELISA kit FMO1 ELISA kit |
| output |
Information sourced from Uniprot.org
