Human Flt3 ligand/Flt3L protein (Recombinant) (C-hFc) (STJP002148)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human FLT3 ligand Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Thr27-Pro185) of Human FLT3 ligand fused with a hFc at the C-terminal.
General Information
| Short Description | Recombinant-Human Flt3 ligand/Flt3L-C-hFc protein was developed in hek293 cells using the region Thr27-Pro185. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | Measured in a cell proliferation assay using Human OCI-AML5 cells. The ED50 for this effect is 1.56-6.24 ng/mL, corresponding to a specific activity of 1.60ร105~6.41ร105 units/mg. |
| Determination Method | < 0.01 EU/Mu g |
Target Information
| Gene Symbol | FLT3LG |
| Gene ID | 2323 |
| Uniprot ID | FLT3L_HUMAN |
| Immunogen | Recombinant Human FLT3 ligand Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Thr27-Pro185) of Human FLT3 ligand fused with a hFc at the C-terminal. |
| Immunogen Region | Thr27-Pro185 |
| Immunogen Sequence | TQDCSFQHSPISSDFAVKIR ELSDYLLQDYPVTVASNLQD EELCGGLWRLVLAQRWMERL KTVAGSKMQGLLERVNTEIH FVTKCAFQPPPSCLRFVQTN ISRLLQETSEQLVALKPWIT RQNFSRCLELQCQPDSSTLP PPWSPRPLEATAPTAPQPP |
Additional Info
| Protein Name | Fms-Related Tyrosine Kinase 3 LigandFlt3 LigandFlt3lSl Cytokine |
| Database Links | Reactome: R-HSA-109704Reactome: R-HSA-1257604Reactome: R-HSA-2219530Reactome: R-HSA-5673001Reactome: R-HSA-6811558Reactome: R-HSA-9607240Reactome: R-HSA-9645135Reactome: R-HSA-9706369Reactome: R-HSA-9706374Reactome: R-HSA-9706377 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Secreted |
| Alternative Protein Names | Fms-Related Tyrosine Kinase 3 Ligand proteinFlt3 Ligand proteinFlt3l proteinSl Cytokine proteinFLT3LG protein |
Information sourced from Uniprot.org