Human Flt3 ligand/Flt3L protein (Recombinant) (C-hFc) (STJP002148)

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STJP002148
£104.50 - £347.50
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Short Description :Recombinant-Human Flt3 ligand/Flt3L-C-hFc protein was developed in hek293 cells using the region Thr27-Pro185. For use in research applications.
Host:HEK293 cells
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation:Unconjugated
Formulation:Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunoreactivity:Measured in a cell proliferation assay using Human OCI-AML5 cells. The ED50 for this effect is 1.56-6.24 ng/mL, corresponding to a specific activity of 1.60×105~6.41×105 units/mg.
Determination Method:< 0.01 EU/Mu g
Gene Symbol:FLT3LG
Gene ID:2323
Uniprot ID:FLT3L_HUMAN
Immunogen:Recombinant Human FLT3 ligand Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Thr27-Pro185) of Human FLT3 ligand fused with a hFc at the C-terminal.
Immunogen Region:Thr27-Pro185
Immunogen Sequence:TQDCSFQHSPISSDFAVKIR ELSDYLLQDYPVTVASNLQD EELCGGLWRLVLAQRWMERL KTVAGSKMQGLLERVNTEIH FVTKCAFQPPPSCLRFVQTN ISRLLQETSEQLVALKPWIT RQNFSRCLELQCQPDSSTLP PPWSPRPLEATAPTAPQPP
Protein Name Fms-Related Tyrosine Kinase 3 Ligand
Flt3 Ligand
Flt3l
Sl Cytokine
Database Links Reactome: R-HSA-109704
Reactome: R-HSA-1257604
Reactome: R-HSA-2219530
Reactome: R-HSA-5673001
Reactome: R-HSA-6811558
Reactome: R-HSA-9607240
Reactome: R-HSA-9645135
Reactome: R-HSA-9706369
Reactome: R-HSA-9706374
Reactome: R-HSA-9706377
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Secreted
Alternative Protein Names Fms-Related Tyrosine Kinase 3 Ligand protein
Flt3 Ligand protein
Flt3l protein
Sl Cytokine protein
FLT3LG protein

Information sourced from Uniprot.org