Human FKBP12.6/FKBP1B protein (Recombinant) (His-Tag) (STJP017390)

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STJP017390
£134.50 - £285.50
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Host: E.coli
Applications: SDS-PAGE/Enzyme Activity
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human FKBP12.6/FKBP1B-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 1mM DTT
Concentration: 0.25 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Immunoreactivity: Specific activity is > 800nmol/min/mg, and is defined as the amount of enzyme cleaves 1nmole of suc-AAPF-pNA per minute at 37C in Tris-HCl pH 8.0 using chymotrypsin.
Gene Symbol: FKBP1B
Gene ID: 2281
Uniprot ID: FKB1B_HUMAN
Immunogen Region: 1-108aa
Accession Number: NP_004107
Immunogen: Human
Immunogen Sequence: MGVEIETI SPGDGRTFPK KGQTCVVHYT GMLQNGKKFD SSRDRNKPFK FRIGKQEVIK GFEEGAAQMS LGQRAKLTCT PDVAYGATGH PGVIPPNATL IFDVELLNLE
Tissue Specificity Detected in heart muscle (at protein level). Isoform 1 and isoform 2 are ubiquitous with highest levels in brain and thymus.
Function Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Protein Name Peptidyl-Prolyl Cis-Trans Isomerase Fkbp1b
Ppiase Fkbp1b
12.6 Kda Fk506-Binding Protein
12.6 Kda Fkbp
Fkbp-12.6
Fk506-Binding Protein 1b
Fkbp-1b
Immunophilin Fkbp12.6
Rotamase
H-Fkbp-12
Database Links Reactome: R-HSA-2672351
Reactome: R-HSA-5578775
Cellular Localisation Cytoplasm
Sarcoplasmic Reticulum
Alternative Protein Names Peptidyl-Prolyl Cis-Trans Isomerase Fkbp1b protein
Ppiase Fkbp1b protein
12.6 Kda Fk506-Binding Protein protein
12.6 Kda Fkbp protein
Fkbp-12.6 protein
Fk506-Binding Protein 1b protein
Fkbp-1b protein
Immunophilin Fkbp12.6 protein
Rotamase protein
H-Fkbp-12 protein
FKBP1B protein
FKBP12.6 protein
FKBP1L protein
FKBP9 protein
OTK4 protein

Information sourced from Uniprot.org

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