Human Fibulin 1 (Fibulin 1) Antibody Pair (STJAP00870)
General Information
| Short Description | This Fibulin 1 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Clone ID | R05-2T-5/R07-3E-7 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purification |
| Dilution Range | Determined by end user |
| Formulation | 0.01M PBS, pH 7.2 |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | FBLN1 |
| Gene ID | 2192 |
| Uniprot ID | FBLN1_HUMAN |
| Immunogen | Recombinant protein |
Additional Info
| Tissue Specificity | Isoform A and isoform B are only expressed in placenta. Isoform C and isoform D are expressed in a variety of tissues and cultured cells. |
| Function | Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. Has been implicated in a role in cellular transformation and tumor invasion, it appears to be a tumor suppressor. May play a role in haemostasis and thrombosis owing to its ability to bind fibrinogen and incorporate into clots. Could play a significant role in modulating the neurotrophic activities of APP, particularly soluble APP. |
| Protein Name | Fibulin-1Fibl-1 |
| Database Links | Reactome: R-HSA-2129379 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Pair Names | Fibulin-1 antibody pairFibl-1 antibody pairFBLN1 antibody pairPP213 antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human Fibulin 1 (Fibulin 1) Antibody Pair (STJAP00870)
This antibody pair detects human Fibulin 1, corresponding to UniProt entry P23142. Reactivity has been confirmed for human samples only.
Both antibodies are rabbit monoclonals, with clone IDs R05-2T-5 and R07-3E-7. Both are supplied as unconjugated IgG, affinity purified, and formulated in 0.01M PBS at pH 7.2.
This antibody pair is validated for use in ELISA. It is intended for sandwich ELISA development, where one clone serves as the capture antibody and the other as the detection antibody.
Optimal working concentrations are determined by the end user and are not pre-specified for this product. Titration experiments are recommended to establish the appropriate concentrations for your specific assay conditions.
The antibodies should be stored at 4°C for short-term use. For long-term storage, aliquot and keep at -20°C, and avoid repeated freeze/thaw cycles.
Both antibodies were raised in rabbit against a recombinant protein immunogen corresponding to human Fibulin 1. No additional immunogen region information is specified for this product.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.