Host: | E. coli |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Recombinant-Human FGF12-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Gene Symbol: | FGF12 |
Gene ID: | 2257 |
Uniprot ID: | FGF12_HUMAN |
Immunogen Region: | Met1-Gly181 |
Immunogen: | Homo sapiens (Human) |
Function | Involved in nervous system development and function. Involved in the positive regulation of voltage-gated sodium channel activity. Promotes neuronal excitability by elevating the voltage dependence of neuronal sodium channel SCN8A fast inactivation. |
Protein Name | Fibroblast Growth Factor 12Fgf-12Fibroblast Growth Factor Homologous Factor 1Fhf-1Myocyte-Activating Factor |
Database Links | Reactome: R-HSA-5576892 |
Cellular Localisation | Nucleus |
Alternative Protein Names | Fibroblast Growth Factor 12 proteinFgf-12 proteinFibroblast Growth Factor Homologous Factor 1 proteinFhf-1 proteinMyocyte-Activating Factor proteinFGF12 proteinFGF12B proteinFHF1 protein |
Information sourced from Uniprot.org