| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of 20mM Tris, 100mM NaCl, pH 8.0. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 0.1 EU/Mu g of the protein by LAL method. |
| Gene Symbol: | FGF21 |
| Gene ID: | 26291 |
| Uniprot ID: | FGF21_HUMAN |
| Immunogen Region: | His29-Ser209 |
| Immunogen: | Recombinant Human FGF-21 Protein is produced by E. coli expression system. The target protein is expressed with sequence (His29-Ser209) of human FGF-21 (Accession #NP_061986.1). |
| Immunogen Sequence: | HPIPDSSPLLQFGGQVRQRY LYTDDAQQTEAHLEIREDGT VGGAADQSPESLLQLKALKP GVIQILGVKTSRFLCQRPDG ALYGSLHFDPEACSFRELLL EDGYNVYQSEAHGLPLHLPG NKSPHRDPAPRGPARFLPLP GLPPALPEPPGILAPQPPDV GSSDPLSMVGPSQGRSPSYA S |
| Function | Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. Regulates systemic glucose homeostasis and insulin sensitivity. |
| Protein Name | Fibroblast Growth Factor 21Fgf-21 |
| Database Links | Reactome: R-HSA-189200Reactome: R-HSA-8963889 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Fibroblast Growth Factor 21 proteinFgf-21 proteinFGF21 proteinUNQ3115 proteinPRO10196 protein |
Information sourced from Uniprot.org
