Human FGD4/FRABP protein (Recombinant) (N-His) (STJP008499)

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STJP008499
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human FGD4/FRABP-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: FGD4
Gene ID: 121512
Uniprot ID: FGD4_HUMAN
Immunogen Region: Ser545-Glu742
Immunogen: Homo sapiens (Human)
Function Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape. Activates MAPK8.
Protein Name Fyve - Rhogef And Ph Domain-Containing Protein 4
Actin Filament-Binding Protein Frabin
Fgd1-Related F-Actin-Binding Protein
Zinc Finger Fyve Domain-Containing Protein 6
Database Links Reactome: R-HSA-193648
Reactome: R-HSA-416482
Reactome: R-HSA-9013148
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Projection
Filopodium
Concentrated In Filopodia And Poorly Detected At Lamellipodia
Binds Along The Sides Of Actin Fibers
Alternative Protein Names Fyve - Rhogef And Ph Domain-Containing Protein 4 protein
Actin Filament-Binding Protein Frabin protein
Fgd1-Related F-Actin-Binding Protein protein
Zinc Finger Fyve Domain-Containing Protein 6 protein
FGD4 protein
FRABP protein
ZFYVE6 protein

Information sourced from Uniprot.org