Function | Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape. Activates MAPK8. |
Protein Name | Fyve - Rhogef And Ph Domain-Containing Protein 4Actin Filament-Binding Protein FrabinFgd1-Related F-Actin-Binding ProteinZinc Finger Fyve Domain-Containing Protein 6 |
Database Links | Reactome: R-HSA-193648Reactome: R-HSA-416482Reactome: R-HSA-9013148 |
Cellular Localisation | CytoplasmCytoskeletonCell ProjectionFilopodiumConcentrated In Filopodia And Poorly Detected At LamellipodiaBinds Along The Sides Of Actin Fibers |
Alternative Protein Names | Fyve - Rhogef And Ph Domain-Containing Protein 4 proteinActin Filament-Binding Protein Frabin proteinFgd1-Related F-Actin-Binding Protein proteinZinc Finger Fyve Domain-Containing Protein 6 proteinFGD4 proteinFRABP proteinZFYVE6 protein |
Information sourced from Uniprot.org