Human FFAR1 protein (Recombinant) (N-His-KSI) (STJP010632)

SKU:
STJP010632
£328.50 - £1,437.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human FFAR1-N-His-KSI protein was developed from e. coli and has a target region of N-His-KSI. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: FFAR1
Gene ID: 2864
Uniprot ID: FFAR1_HUMAN
Immunogen Region: [Glu65-Cys79] & [Gly143-Ser178] & [Cys201-Ala223] & [Gly280-Lys300]
Immunogen: Homo sapiens (Human)
Function G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis.receptor signaling activates pathways that inhibit osteoclast differentiation. Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway. Mediates the anti-inflammatory effects of omega-3 polyunsaturated fatty acids (PUFAs) via inhibition of NLRP3 inflammasome activation.
Protein Name Free Fatty Acid Receptor 1
G-Protein Coupled Receptor 40
Database Links Reactome: R-HSA-381771
Reactome: R-HSA-400511
Reactome: R-HSA-416476
Reactome: R-HSA-434316
Reactome: R-HSA-444209
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Free Fatty Acid Receptor 1 protein
G-Protein Coupled Receptor 40 protein
FFAR1 protein
GPR40 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP010918 Human DEFB1 protein (Recombinant) (N-His-KSI) (STJP010918) E. coli
STJP010922 Human SLC6A3 protein (Recombinant) (N-His-KSI) (STJP010922) E. coli
STJP011013 Human SLC9A9 protein (Recombinant) (N-His-KSI) (STJP011013) E. coli
STJP010861 Human SLC25A4 protein (Recombinant) (N-His-KSI) (STJP010861) E. coli
STJP010849 Human ZNF688 protein (Recombinant) (N-His-KSI) (STJP010849) E. coli

Related Products

!