• Human Fetuin A/AHSG protein (Recombinant) (C-His) (STJP000968)
  • Human Fetuin A/AHSG protein (Recombinant) (C-His) (STJP000968)
  • Human Fetuin A/AHSG protein (Recombinant) (C-His) (STJP000968)
  • Human Fetuin A/AHSG protein (Recombinant) (C-His) (STJP000968)

Human Fetuin A/AHSG protein (Recombinant) (C-His) (STJP000968)

SKU:
STJP000968

£72.50 - £224.50
Current Stock:
Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Formulation: Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: < 0.1 EU/Mu g of the protein by LAL method.
Immunoreactivity: 1.Measured by its ability to inhibit calcium phosphate precipitation. The IC50 value is <25 Mu g/mL.
Gene Symbol: AHSG
Gene ID: 197
Uniprot ID: FETUA_HUMAN
Immunogen: Recombinant Human Fetuin A/AHSG Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala19-Val367) of human Fetuin-A/AHSG/FETUA (Accession #NP_001613.2) fused with a 6×His tag at the C-terminus.
Immunogen Sequence: APHGPGLIYRQPNCDDPETE EAALVAIDYINQNLPWGYKH TLNQIDEVKVWPQQPSGELF EIEIDTLETTCHVLDPTPVA RCSVRQLKEHAVEGDCDFQL LKLDGKFSVVYAKCDSSPDS AEDVRKVCQDCPLLAPLNDT RVVHAAKAALAAFNAQNNGS NFQLEEISRAQLVPLPPSTY VEFTVSGTDCVAKEATEAAK CNLLAEKQYGFCKATLSEKL GGAEVAVTCMVFQTQPVSS
Tissue Specificity Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins.
Post Translational Modifications Phosphorylated by FAM20C in the extracellular medium. O- and N-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. N-glycan at Asn-156: Hex5HexNAc4.N-glycan heterogeneity at Asn-176: Hex5HexNAc4 (major) and Hex6HexNAc5 (minor).
Function Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions.
Protein Name Alpha-2-Hs-Glycoprotein
Alpha-2-Z-Globulin
Ba-Alpha-2-Glycoprotein
Fetuin-A Cleaved Into - Alpha-2-Hs-Glycoprotein Chain A - Alpha-2-Hs-Glycoprotein Chain B
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-381426
Reactome: R-HSA-6798695
Reactome: R-HSA-8957275
Cellular Localisation Secreted
Alternative Protein Names Alpha-2-Hs-Glycoprotein
Alpha-2-Z-Globulin protein
Ba-Alpha-2-Glycoprotein
Fetuin-A Cleaved Into - Alpha-2-Hs-Glycoprotein Chain A - Alpha-2-Hs-Glycoprotein Chain B protein
AHSG protein
FETUA protein
PRO2743 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance