Host: |
HEK293 cells |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Recombinant-Human Fetuin A/AHSG-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation. |
Immunoreactivity: |
Measured by its ability to inhibit calcium phosphate precipitation. The IC50 value is |
Gene Symbol: |
AHSG |
Gene ID: |
197 |
Uniprot ID: |
FETUA_HUMAN |
Immunogen: |
Recombinant Human Fetuin A/AHSG Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala19-Val367) of human Fetuin-A/AHSG/FETUA (Accession #NP_001613.2) fused with a 6×His tag at the C-terminus. |
Tissue Specificity | Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins. |
Post Translational Modifications | Phosphorylated by FAM20C in the extracellular medium. O- and N-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. N-glycan at Asn-156: Hex5HexNAc4.N-glycan heterogeneity at Asn-176: Hex5HexNAc4 (major) and Hex6HexNAc5 (minor). |
Function | Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions. |
Protein Name | Alpha-2-Hs-GlycoproteinAlpha-2-Z-GlobulinBa-Alpha-2-GlycoproteinFetuin-A Cleaved Into - Alpha-2-Hs-Glycoprotein Chain A - Alpha-2-Hs-Glycoprotein Chain B |
Database Links | Reactome: R-HSA-114608Reactome: R-HSA-381426Reactome: R-HSA-6798695Reactome: R-HSA-8957275 |
Cellular Localisation | Secreted |
Alternative Protein Names | Alpha-2-Hs-GlycoproteinAlpha-2-Z-Globulin proteinBa-Alpha-2-GlycoproteinFetuin-A Cleaved Into - Alpha-2-Hs-Glycoprotein Chain A - Alpha-2-Hs-Glycoprotein Chain B proteinAHSG proteinFETUA proteinPRO2743 protein |
Information sourced from Uniprot.org
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