| Host: |
E.coli |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: |
Lyophilised from a 0.2 Mu m filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: |
< 1 EU/Mu g of the protein by LAL method. |
| Gene Symbol: |
FTH1 |
| Gene ID: |
2495 |
| Uniprot ID: |
FRIH_HUMAN |
| Immunogen Region: |
Met1-Ser183 |
| Immunogen: |
Recombinant Human Ferritin heavy chain/FTH1 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Met1-Ser183) of human Ferritin heavy chain/FTH1 (Accession #P02794). |
| Immunogen Sequence: |
QALGQDMVSPEATNSSSSSF SSPSSAGRHVRSYNHLQGDV RWRKLFSFTKYFLKIEKNGK VSGTKKENCPYSILEITSVE IGVVAVKAINSNYYLAMNKK GKLYGSKEFNNDCKLKERIE ENGYNTYASFNWQHNGRQMY VALNGKGAPRRGQKTRRKNT SAHFLPMVVHS |
| Tissue Specificity | Expressed in the liver. |
| Function | Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. Delivery to lysosomes is mediated by the cargo receptor NCOA4 for autophagic degradation and release of iron. |
| Protein Name | Ferritin Heavy ChainFerritin H SubunitCell Proliferation-Inducing Gene 15 Protein Cleaved Into - Ferritin Heavy Chain - N-Terminally Processed |
| Database Links | Reactome: R-HSA-3000480Reactome: R-HSA-432722Reactome: R-HSA-6798695Reactome: R-HSA-917937 |
| Cellular Localisation | CytoplasmLysosomeCytoplasmic VesicleAutophagosome |
| Alternative Protein Names | Ferritin Heavy Chain proteinFerritin H Subunit proteinCell Proliferation-Inducing Gene 15 Protein Cleaved Into - Ferritin Heavy Chain - N-Terminally Processed proteinFTH1 proteinFTH proteinFTHL6 proteinOK proteinSW-cl.84 proteinPIG15 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
