Human FceRII (Receptor II For The Fc Region Of Immunoglobulin E) Sandwich ELISA Kit (STJE0008824)
SPECIFICATIONS
General Information
| Short Description | This FceRII Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.107ng/mL |
| Detection Limit | 0.312-20ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | FCER2 |
| Gene ID | 2208 |
| Uniprot ID | FCER2_HUMAN |
| Sample Type | serum, plasma or other biological fluids. |
Additional Info
| Tissue Specificity | Detected in urine (at protein level). |
| Post Translational Modifications | N- and O-glycosylated. The secreted form sCD23 is produced by ADAM10-mediated ectodomain shedding. |
| Function | Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells. On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine-nitric oxide pathway. |
| Protein Name | Low Affinity Immunoglobulin Epsilon Fc ReceptorBlast-2C-Type Lectin Domain Family 4 Member JFc-Epsilon-RiiImmunoglobulin E-Binding FactorLymphocyte Ige ReceptorCd Antigen Cd23 Cleaved Into - Low Affinity Immunoglobulin Epsilon Fc Receptor Membrane-Bound Form - Low Affinity Immunoglobulin Epsilon Fc Receptor Soluble Form |
| Database Links | Reactome: R-HSA-2197563Reactome: R-HSA-6783783Reactome: R-HSA-6785807 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinLipid-AnchorSecretedAlso Exists As A Soluble Excreted FormScd23 |
| Alternative ELISA Names | Low Affinity Immunoglobulin Epsilon Fc Receptor ELISA kitBlast-2 ELISA kitC-Type Lectin Domain Family 4 Member J ELISA kitFc-Epsilon-Rii ELISA kitImmunoglobulin E-Binding Factor ELISA kitLymphocyte Ige Receptor ELISA kitCd Antigen Cd23 Cleaved Into - Low Affinity Immunoglobulin Epsilon Fc Receptor Membrane-Bound Form - Low Affinity Immunoglobulin Epsilon Fc Receptor Soluble Form ELISA kitFCER2 ELISA kitCD23A ELISA kitCLEC4J ELISA kitFCE2 ELISA kitIGEBF ELISA kit |
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Information sourced from Uniprot.org