• Biotinylated Human Fc gamma RIIA/CD32a (R167) on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
  • The purity of Biotinylated Fc gamma RIIA/CD32a (R167) is greater than 95% as determined by SEC-HPLC.
  • Rituximab captured on CM5 Chip via Protein A can bind Biotinylated Human Fc gamma RIIA (R167) , His-Avi Tag with an affinity constant of 1. 03 Mu M as determined in SPR assay (Biacore T200).

Human Fc gamma RIIA/CD32a (R167) protein (Recombinant) (C-His-Avi) {Biotin} (STJP001608)

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STJP001608

£618.50 - £1,909.50
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Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human Fc gamma RIIA/CD32a (R167)-C-His-Avi protein was developed from hek293 and has a target region of C-His-Avi. For use in research applications.
Conjugation: Biotin
Formulation: Lyophilised from 0.2 µm filtered PBS solution pH7.4.
Dilution Range: Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM
Storage Instruction: The lyophilized protein is stable for at least 1 year from date of receipt at-20°C.
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg).
Gene Symbol: FCGR2A
Gene ID: 2212
Uniprot ID: FCG2A_HUMAN
Immunogen Region: Ala36-Ile218
Immunogen: DNA sequence encoding Human Fc gamma RIIA/CD32a (R167) including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.
Post Translational Modifications Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK.
Function Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.
Protein Name Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A
Igg Fc Receptor Ii-A
Cdw32
Fc-Gamma Rii-A
Fc-Gamma-Riia
Fcrii-A
Cd Antigen Cd32
Database Links Reactome: R-HSA-2029481
Reactome: R-HSA-2029482
Reactome: R-HSA-2029485
Reactome: R-HSA-6798695
Reactome: R-HSA-9664323
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A protein
Igg Fc Receptor Ii-A protein
Cdw32 protein
Fc-Gamma Rii-A protein
Fc-Gamma-Riia protein
Fcrii-A protein
Cd Antigen Cd32 protein
FCGR2A protein
CD32 protein
FCG2 protein
FCGR2A1 protein
IGFR2 protein

Information sourced from Uniprot.org

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