Human FBP2 protein (Recombinant) (N-His) (STJP003173)

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STJP003173
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human FBP2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: FBP2
Gene ID: 8789
Uniprot ID: F16P2_HUMAN
Immunogen Region: Met1-Leu212
Immunogen: Homo sapiens (Human)
Function Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate.
Protein Name Fructose-1 -6-Bisphosphatase Isozyme 2
Fbpase 2
D-Fructose-1 -6-Bisphosphate 1-Phosphohydrolase 2
Muscle Fbpase
Database Links Reactome: R-HSA-70263
Cellular Localisation Cell Junction
Cytoplasm
Nucleus
Myofibril
Sarcomere
Z Line
In Neonatal Cardiomyocytes
Distributed Throughout The Cytosol
Accumulating In The Intercalated Disks Which Occur At The Z Line Of Cardiomyocytes And Connect Adjacent Cells
And Also Located In The Nucleus
Dissociates From The Z Line Following An Increase In Cytosolic Ca(2+) Concentration
In Muscle Precursor Cells
Localizes Predominantly To The Nucleus And To A Lesser Extent To The Cytoplasm At The Proliferative Phase
While Mainly Localizing To The Cytoplasm At The Differentiation Phase
Colocalizes With Aldoa And Alpha-Actinin On Both Sides Of The Z Line Of Skeletal Muscle
Dissociates Rapidly From The Z Line Following An Increase In Cytosolic Ca(2+) Concentration
Alternative Protein Names Fructose-1 -6-Bisphosphatase Isozyme 2 protein
Fbpase 2 protein
D-Fructose-1 -6-Bisphosphate 1-Phosphohydrolase 2 protein
Muscle Fbpase protein
FBP2 protein

Information sourced from Uniprot.org