Human FBLN5 protein (Recombinant) (N-His) (STJP006140)

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STJP006140
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human FBLN5-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: FBLN5
Gene ID: 10516
Uniprot ID: FBLN5_HUMAN
Immunogen Region: Leu99-Cys205
Immunogen: Homo sapiens (Human)
Post Translational Modifications N-glycosylated.
Function Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN. Stabilizes and organizes elastic fibers in the skin, lung and vasculature. Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling. May act as an adapter that mediates the interaction between FBN1 and ELN.
Protein Name Fibulin-5
Fibl-5
Developmental Arteries And Neural Crest Egf-Like Protein
Dance
Urine P50 Protein
Up50
Database Links Reactome: R-HSA-1566948
Reactome: R-HSA-2129379
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Co-Localizes With Eln In Elastic Fibers
Alternative Protein Names Fibulin-5 protein
Fibl-5 protein
Developmental Arteries And Neural Crest Egf-Like Protein protein
Dance protein
Urine P50 Protein protein
Up50 protein
FBLN5 protein
DANCE protein
UNQ184 protein
PRO210 protein

Information sourced from Uniprot.org

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