| Short Description : | Recombinant-Human FARS2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 0.5 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% Glycerol, 1mM EDTA, 0.1M NaCl |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FARS2 |
| Gene ID: | 10667 |
| Uniprot ID: | SYFM_HUMAN |
| Accession Number: | NP_006558.1 |
| Immunogen: | Human |
| Immunogen Region: | 37-451aa |
| Immunogen Sequence: |
| Function | Is responsible for the charging of tRNA(Phe) with phenylalanine in mitochondrial translation. To a lesser extent, also catalyzes direct attachment of m-Tyr (an oxidized version of Phe) to tRNA(Phe), thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins. |
| Protein Name | Phenylalanine--Trna Ligase - MitochondrialPhenylalanyl-Trna SynthetasePhers |
| Database Links | Reactome: R-HSA-379726 |
| Cellular Localisation | Mitochondrion MatrixMitochondrion |
| Alternative Protein Names | Phenylalanine--Trna Ligase - Mitochondrial proteinPhenylalanyl-Trna Synthetase proteinPhers proteinFARS2 proteinFARS1 proteinHSPC320 protein |
Information sourced from Uniprot.org