Tissue Specificity | Highly expressed in the pancreas. Also found in the colon, kidney, prostate, small intestine and testis. |
Post Translational Modifications | 2 N-termini have been observed in the mature protein: the first at Glu-30, resulting from signal peptide cleavage, the second at Ser-46. O-glycosylated. |
Function | Induces apoptosis of alpha and beta cells in a dose- and time-dependent manner. |
Protein Name | Protein Fam3bCytokine-Like Protein 2-21Pancreatic-Derived FactorPander |
Database Links | |
Cellular Localisation | SecretedPresent In Insulin Secretory Granules And Likely Cosecreted With InsulinLocalized In Discrete Vesicular And Perinuclear Structure |
Alternative ELISA Names | Protein Fam3b ELISA kitCytokine-Like Protein 2-21 ELISA kitPancreatic-Derived Factor ELISA kitPander ELISA kitFAM3B ELISA kitC21orf11 ELISA kitC21orf76 ELISA kitPRED44 ELISA kitUNQ320 ELISA kitPRO365 ELISA kit |
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Information sourced from Uniprot.org