Human FAHD1 protein (Recombinant) (N-His) (STJP016012)

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STJP016012
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Host: E.coli
Applications: ELISA/Immunogen/SDS-PAGE/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human FAHD1-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: Please contact us for further information.
Gene Symbol: FAHD1
Gene ID: 81889
Uniprot ID: FAHD1_HUMAN
Immunogen Region: Ala25-Tyr221
Immunogen: Homo sapiens (Human)
Function Tautomerase that converts enol-oxaloacetate, a strong inhibitor of succinate dehydrogenase, to the physiological keto form of oxaloacetate. It is thereby required to maximize aerobic respiration efficiency by preventing succinate dehydrogenase inhibition. Also acts as a weak oxaloacetate decarboxylase (ODx), catalyzing the decarboxylation of oxaloacetate (OAA) to pyruvate and CO(2), and as such is likely a regulatory enzyme in the TCA cycle. Also displays acylpyruvase activity, being able to hydrolyze acetylpyruvate and fumarylpyruvate in vitro. Exhibits only a weak hydrolase activity on methylacetopyruvate and acetylacetone, and no activity toward acetoacetyl-CoA.
Protein Name Oxaloacetate Tautomerase Fahd1 - Mitochondrial
Acylpyruvase Fahd1
Fumarylacetoacetate Hydrolase Domain-Containing Protein 1
Fah Domain-Containing Protein 1
Oxaloacetate Decarboxylase
Oaa Decarboxylase
Odx
Yisk-Like Protein
Database Links Reactome: R-HSA-70268
Cellular Localisation Mitochondrion
Cytoplasm
Cytosol
Alternative Protein Names Oxaloacetate Tautomerase Fahd1 - Mitochondrial protein
Acylpyruvase Fahd1 protein
Fumarylacetoacetate Hydrolase Domain-Containing Protein 1 protein
Fah Domain-Containing Protein 1 protein
Oxaloacetate Decarboxylase protein
Oaa Decarboxylase protein
Odx protein
Yisk-Like Protein protein
FAHD1 protein
C16orf36 protein
YISKL protein

Information sourced from Uniprot.org