Human FABP6 protein (Recombinant) (N-His) (STJP007902)

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STJP007902
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human FABP6-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: FABP6
Gene ID: 2172
Uniprot ID: FABP6_HUMAN
Immunogen Region: Met1-Ala128
Immunogen: Homo sapiens (Human)
Function Binds to bile acids and is involved in enterohepatic bile acid metabolism. Required for efficient apical to basolateral transport of conjugated bile acids in ileal enterocytes. In vitro binds to bile acids in the order: deoxycholic acid > cholic acid > chenodeoxycholic acid and respective BA conjugation modifies affinities in the order taurine-conjugated > glycine-conjugated > unconjugated bile acids. Stimulates gastric acid and pepsinogen secretion. Isoform 2: Essential for the survival of colon cancer cells to bile acid-induced apoptosis.
Protein Name Gastrotropin
Gt
Fatty Acid-Binding Protein 6
Ileal Lipid-Binding Protein
Ilbp
Intestinal 15 Kda Protein
I-15p
Intestinal Bile Acid-Binding Protein
I-Babp
Database Links Reactome: R-HSA-159418
Reactome: R-HSA-163560
Reactome: R-HSA-9623433
Cellular Localisation Isoform 1: Cytoplasm
Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Isoform 2: Cytoplasm
Localized Close To Nucleus On The Apical Side Of Both Normal And Neoplastic Cells
Alternative Protein Names Gastrotropin protein
Gt protein
Fatty Acid-Binding Protein 6 protein
Ileal Lipid-Binding Protein protein
Ilbp protein
Intestinal 15 Kda Protein protein
I-15p protein
Intestinal Bile Acid-Binding Protein protein
I-Babp protein
FABP6 protein
ILBP protein
ILLBP protein

Information sourced from Uniprot.org