Human FABP2/I-FABP protein (Recombinant) (No-Tag) (STJP003037)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenRecombinant Recombinant Human FABP2/I-FABP Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala2-Asp132) of Human FABP2/I-FABP (Accession #NP_000125.2) fused with a His tag at the N-terminus.
General Information
| Short Description | Recombinant-Human FABP2/I-FABP-No-Tag protein was developed in e.coli using the region Ala2-Asp132. For use in research applications. |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from 0.22 Mu m filtered solution in PBS (pH 7.4). Normally 8% Trehalose is added as protectant before lyophilisation. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 0.01 EU/Mu g of the protein by LAL method |
Target Information
| Gene Symbol | FABP2 |
| Gene ID | 2169 |
| Uniprot ID | FABPI_HUMAN |
| Immunogen | Recombinant Recombinant Human FABP2/I-FABP Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala2-Asp132) of Human FABP2/I-FABP (Accession #NP_000125.2) fused with a His tag at the N-terminus. |
| Immunogen Region | Ala2-Asp132 |
| Immunogen Sequence | CGLVASNLNLKPGECLKVRG EVASDAKSFVLNLGKDSNNL CLHFNPRFNAHGDANTIVCN TKEDGTWGTEHREPAFPFQP GSITEVCITFDQADLTIKLP DGHEFKFPNRLNMEAINYMA ADGDFKIKCVAFE |
Additional Info
| Tissue Specificity | Expressed in the small intestine and at much lower levels in the large intestine. Highest expression levels in the jejunum. |
| Function | FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor. |
| Protein Name | Fatty Acid-Binding Protein - IntestinalFatty Acid-Binding Protein 2Intestinal-Type Fatty Acid-Binding ProteinI-Fabp |
| Database Links | Reactome: R-HSA-163560 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Fatty Acid-Binding Protein - Intestinal proteinFatty Acid-Binding Protein 2 proteinIntestinal-Type Fatty Acid-Binding Protein proteinI-Fabp proteinFABP2 proteinFABPI protein |
Information sourced from Uniprot.org