Human F12 protein (Recombinant) (N-His) (STJP003490)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human F12-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | F12 |
| Gene ID | 2161 |
| Uniprot ID | FA12_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met316-Ser615 |
Additional Info
| Function | Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa. |
| Protein Name | Coagulation Factor XiiHageman FactorHaf Cleaved Into - Coagulation Factor Xiia Heavy Chain - Beta-Factor Xiia Part 1 - Coagulation Factor Xiia Light ChainBeta-Factor Xiia Part 2 |
| Database Links | Reactome: R-HSA-140837Reactome: R-HSA-9657688Reactome: R-HSA-9657689 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Coagulation Factor Xii proteinHageman Factor proteinHaf Cleaved Into - Coagulation Factor Xiia Heavy Chain - Beta-Factor Xiia Part 1 - Coagulation Factor Xiia Light Chain proteinBeta-Factor Xiia Part 2 proteinF12 protein |
Information sourced from Uniprot.org