Human F12 protein (Recombinant) (N-His) (STJP003490)

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STJP003490
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human F12-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: F12
Gene ID: 2161
Uniprot ID: FA12_HUMAN
Immunogen Region: Met316-Ser615
Immunogen: Homo sapiens (Human)
Function Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa.
Protein Name Coagulation Factor Xii
Hageman Factor
Haf Cleaved Into - Coagulation Factor Xiia Heavy Chain - Beta-Factor Xiia Part 1 - Coagulation Factor Xiia Light Chain
Beta-Factor Xiia Part 2
Database Links Reactome: R-HSA-140837
Reactome: R-HSA-9657688
Reactome: R-HSA-9657689
Cellular Localisation Secreted
Alternative Protein Names Coagulation Factor Xii protein
Hageman Factor protein
Haf Cleaved Into - Coagulation Factor Xiia Heavy Chain - Beta-Factor Xiia Part 1 - Coagulation Factor Xiia Light Chain protein
Beta-Factor Xiia Part 2 protein
F12 protein

Information sourced from Uniprot.org

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